Ankylosing Spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and reduced mobility.

Understanding Ankylosing Spondylitis: Causes, Symptoms, and Treatments

There are more than 16 Lakh people currently in India who are suffering from Ankylosing Spondylitis (AS), a number which continues to rise. It is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and reduced mobility. Over time, it can lead to the fusion of vertebrae, significantly impacting posture and daily activities.

While AS has no definitive cure, early diagnosis and proper management can help control symptoms and improve quality of life. Let’s explore the causes, symptoms, and treatment options available to help individuals effectively manage Ankylosing Spondylitis.

What is Ankylosing Spondylitis?

Ankylosing Spondylitis is a type of arthritis that mainly affects the spine and sacroiliac joints (where the spine meets the pelvis).

  • It causes inflammation in these areas, leading to pain, stiffness, and, in severe cases, the fusion of spinal vertebrae. This fusion can result in a rigid, hunched posture, limiting flexibility and movement.
  • It can also affect other joints, such as the hips, shoulders, and ribs, and may even impact the eyes and cardiovascular system in some cases.

Causes of Ankylosing Spondylitis

The exact cause of AS remains unknown, but researchers believe that a combination of genetic and environmental factors contributes to its development.

Genetic Factors

The HLA-B27 gene has been linked to the occurrence of Ankylosing Spondylitis. People with this gene have a higher risk of developing AS, although not everyone with the gene will experience the disease.

Immune System Dysfunction

AS is classified as an autoimmune disorder, meaning the immune system mistakenly attacks healthy tissues, causing inflammation in the spine and joints.

Environmental Triggers

Certain environmental factors, such as infections or bacterial exposure, may trigger AS in genetically susceptible individuals.

Symptoms of Ankylosing Spondylitis

AS symptoms vary from person to person, but common signs include:

  • Chronic Back Pain and Stiffness: Persistent pain in the lower back and hips, often worsening in the morning or after inactivity.
  • Reduced Flexibility and Postural Changes: Over time, inflammation can lead to spinal fusion, reducing mobility and causing a hunched-forward posture.
  • Fatigue: The body’s continuous inflammatory response can result in extreme fatigue and a general feeling of discomfort.
  • Pain in Other Joints: AS may also cause pain and stiffness in the shoulders, hips, knees, and ribs.
  • Eye and Cardiovascular Complications: Some individuals experience eye inflammation (uveitis), leading to redness, pain, and vision issues. AS may also increase the risk of heart disease.

Diagnosis of Ankylosing Spondylitis

Early diagnosis is crucial in preventing severe complications. Doctors use a combination of methods to confirm AS:

1. Physical Examination: A doctor assesses spinal mobility, posture, and tenderness in affected areas.

2. Imaging Tests: X-rays can show changes in the sacroiliac joints and spine, while MRI scans help detect early inflammation.

3. Blood Tests: Tests for markers of inflammation (such as C-reactive protein) and the presence of the HLA-B27 gene may aid in diagnosis.

Treatment Options for Ankylosing Spondylitis

While there is no cure for AS, several treatment options help manage pain, reduce inflammation, and improve mobility.

Non-Surgical Treatments

Non-surgical methods are often the first line of treatment for AS, offering effective relief without the risks of surgery.

Medications:

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Help reduce pain and inflammation.
  • Biologic Medications (TNF Inhibitors, IL-17 Inhibitors): Target inflammation pathways to slow disease progression.
  • Pain Relievers and Muscle Relaxants: Provide short-term relief from muscle tightness and discomfort.

Physiotherapy and Rehabilitation: 

  • Specific exercises strengthen the back and core muscles, improving posture and spinal flexibility.
  • Stretching routines help reduce stiffness and enhance movement.

Spinal Decompression Treatment:

  • This non-invasive treatment helps relieve pressure on spinal discs, improving spinal alignment and reducing pain.
  • It is particularly beneficial for those experiencing nerve compression due to AS.

Chiropractic Care: 

  • Spinal adjustments can relieve tension in affected joints, enhancing mobility and reducing discomfort.
  • Chiropractic therapy focuses on posture correction and spinal alignment to prevent worsening symptoms.
Lifestyle Modifications

Making simple lifestyle adjustments can significantly improve the quality of life for AS patients.

  • Posture Correction: Maintaining proper posture while sitting and standing can help prevent spinal deformities.
  • Low-Impact Exercise: Activities like swimming, yoga, and stretching help improve flexibility and relieve stiffness.
  • Ergonomic Adjustments: Using a supportive mattress, ergonomic chairs, and proper work setups can reduce spinal strain.
  • Healthy Diet and Weight Management: Maintaining a healthy weight reduces stress on the spine and joints.

Managing Ankylosing Spondylitis for Long-Term Health

Effective AS management requires a proactive approach, including:

Early Intervention

Seeking medical advice on the first signs of persistent back pain can help slow disease progression.

Consistent Exercise Routine

Regular movement prevents stiffness, improves flexibility, and strengthens spinal muscles.

Regular Monitoring

Periodic check-ups with doctors ensure early detection of complications and allow adjustments to treatment plans.

Support and Awareness

Joining AS support groups and staying informed about new treatment options can empower patients to take control of their condition.

About ANSSI:

ANSSI Wellness focuses on improving the quality of life for patients suffering from spinal issues, aiming to provide relief where other conventional treatments have failed. Through advanced non-surgical spinal decompression treatment, ANSSI is committed to helping patients avoid surgery and recover in a safe, effective, and compassionate environment.

Connect with ANSSI Wellness on LinkedIn, Instagram, and Facebook for expert guidance.

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